Shanghai AQ BioPharma is A leading company specializing on the fluorine containing drug discovery and fluorinated intermediates/chemicalsmanufacture in china。Our feature products including: fluorinated drug intermediate; piperidine; piperazine; pyrrolidine; azaindole,adamantane,azaspiro- and azafused heterocycles etc.
PUIRTY:>95%
Tert-butyl 4-(2,2,2-trifluoro-1-hydroxyethyl)piperidine-1-carboxylate (CAS: 1058976-86-7) is a specialized fluorinated piperidine intermediate. Synthesized via nucleophilic addition of trifluoroacetaldehyde to protected piperidine, this compound features the molecular formula C10H16F3NO2. It serves as a critical building block for introducing trifluoromethylcarbinol motifs into complex pharmaceutical scaffolds.
Store under inert atmosphere at -20°C to prevent hydrolysis. Personnel must utilize chemical-resistant PPE due to potential respiratory irritation from fluorinated vapors. Strict adherence to GMP guidelines is required for clinical-grade batches.