Category:
Other Specialized Reagents
Standard:
In-house Standards,
TFA-EO Linker denotes a trifluoroacetic acid-cleavable polyethylene glycol spacer used in peptide synthesis. It facilitates the attachment of functional groups via ether bonds, enabling precise deprotection under acidic conditions. The general molecular structure features repeating ethylene oxide units terminated by a TFA-labile group.
Store at -20°C in a dry, inert atmosphere to prevent hydrolysis. Handle with appropriate PPE due to potential sensitization and corrosive degradation products upon cleavage. Avoid exposure to strong acids outside intended synthetic protocols.