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Overview
Tigecycline is a broad-spectrum tetracycline-class antibiotic synthesized via semi-synthetic modification of minocycline. Its molecular formula is C29H39N5O8 with CAS number 220621-74-3.
Application
- Infectious Disease Management: Treatment of complicated skin infections and intra-abdominal infections.
- Antimicrobial Resistance: Effective against multidrug-resistant Gram-positive and Gram-negative bacteria.
- Hospital Settings: Used as a last-resort therapy for severe nosocomial pneumonia.
Precautions
Strictly contraindicated in children under eight years due to tooth discoloration risks. Requires refrigerated storage at 2°C–8°C for stability. Monitor hepatic function during prolonged IV infusion protocols.