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Overview
Tiopronin (2-mercapto-propionylglycine) is a cysteine analogue used primarily in urology and nephrology. Manufactured via chemical synthesis, its molecular formula is C5H9NO3S and CAS No. 967-49-3.
Application
- Dissolution of calcium oxalate kidney stones in patients with recurrent cystinuria.
- Preventive therapy for radiopaque contrast media-induced nephropathy.
- Adjunct treatment in heavy metal poisoning cases involving lead or mercury.
Precautions
Contraindicated in patients with severe renal failure or hypersensitivity to sulfhydryl compounds. Store in a cool, dry place below 25°C, protected from light. Strict adherence to dosage protocols is required to avoid potential hematological side effects.