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Overview
Tiotropium Bromide Monohydrate is a long-acting muscarinic antagonist (LAMA) produced via bromination and crystallization. Its molecular formula is C20H24NO3Br·H2O, with CAS No. 119682-45-2.
Application
- Pulmonary medicine for maintenance treatment of COPD.
- Asthma management as an adjunct bronchodilator therapy.
- Pharmaceutical manufacturing for dry powder inhalers (DPIs).
Precautions
Contraindicated in patients with hypersensitivity to atropine derivatives. Store in tightly sealed containers below 25°C to prevent hydration loss. Handle with respiratory protection during bulk processing.