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Overview
Toceranib Phosphate is a small-molecule tyrosine kinase inhibitor (TKI) developed for veterinary oncology. It targets VEGFR, PDGFR, and c-KIT to inhibit tumor angiogenesis and proliferation. The compound features a phosphate salt form enhancing solubility compared to the free base. Molecular Formula: C24H25F2N7O3P; CAS No.: 1016879-75-4.
Application
- Veterinary medicine: Treatment of mast cell tumors in dogs.
- Oncology research: Preclinical studies on receptor tyrosine kinases.
- Pharmaceutical manufacturing: Active Pharmaceutical Ingredient (API) production.
Precautions
- Restricted to veterinary use only; not approved for human clinical trials.
- Store under controlled conditions (2°C–8°C) to maintain stability.
- Handle with appropriate PPE to avoid dermal exposure or inhalation.