Category:
Active Pharmaceutical Ingredients
CAS NO:
540737-29-9
Standard:
In-house Standards,
Tofacitinib Citrate is a pharmaceutical intermediate defined as the citric acid salt of tofacitinib, a Janus kinase (JAK) inhibitor. It is synthesized via salt formation between tofacitinib free base and citric acid to enhance stability and solubility. The molecular formula is C16H24N8O7P and CAS number is 1259087-28-7.
Contraindicated in patients with active serious infections or severe hepatic impairment. Requires storage in sealed containers at controlled room temperature (20°C–25°C) away from moisture. Strict adherence to GMP standards is mandatory during manufacturing to ensure potency and safety.