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Overview
Tofacitinib (CP-690550, Tasocitinib) is a potent, orally bioavailable JAK1/JAK3 inhibitor used in immunology. Molecular formula: C17H21N6O4P; CAS: 486908-91-2.
Application
- Rheumatoid arthritis treatment as monotherapy or combination with methotrexate.
- Psoriatic arthritis management for symptom control and joint protection.
- Ulcerative colitis therapy for inducing and maintaining clinical remission.
Precautions
Contraindicated in active serious infections; requires monitoring for thrombosis, malignancy, and lipid levels. Store at controlled room temperature (20-25°C) in moisture-proof containers.