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Overview
Tolvaptan is a selective vasopressin V2 receptor antagonist used to treat hyponatremia and polycystic kidney disease. Molecular Formula: C24H27ClN4O5; CAS No: 196068-29-4.
Application
- Pharmaceutical Manufacturing: Active pharmaceutical ingredient (API) for oral tablets.
- Nephrology: Management of euvolemic and hypervolemic hyponatremia.
- Polycystic Kidney Disease: Slowing cyst growth and kidney function decline.
Precautions
Contraindicated in anuria, severe hepatic impairment, or concomitant use with strong CYP3A inhibitors. Requires strict liver function monitoring during treatment. Store in a cool, dry place protected from light.