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Overview
Trastuzumab is a recombinant humanized monoclonal antibody targeting the HER2 receptor. Produced via CHO cell fermentation, its molecular formula is C6548H10079N1691O2027S44 with CAS No. 180277-26-1.
Application
- Targeted therapy for HER2-positive metastatic breast cancer.
- Treatment of early-stage HER2+ breast cancer in combination with chemotherapy.
- Management of metastatic gastric or gastroesophageal junction adenocarcinoma.
Precautions
Contraindicated in patients with severe hypersensitivity to the drug or murine proteins. Strictly store at 2°C to 8°C; do not freeze. Monitor for cardiotoxicity and infusion reactions during clinical administration.