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Overview
Treagliptin (CAS 865759-25-7) is a potent, long-acting dipeptidyl peptidase-4 (DPP-4) inhibitor developed for type 2 diabetes management. Synthesized via advanced heterocyclic coupling, its molecular formula is C19H25N5O3. This API offers superior metabolic stability compared to earlier generation inhibitors.
Application
- Pharmaceutical Manufacturing: Primary active ingredient in oral antidiabetic formulations.
- Metabolic Research: Used in clinical trials to evaluate glucose homeostasis mechanisms.
- Quality Control: Reference standard for HPLC assay validation in diabetes therapeutics.
Precautions
Strictly regulated as a pharmaceutical intermediate; requires storage below -20°C under inert atmosphere. Clinical use mandates monitoring for hypersensitivity reactions and pancreatitis risks. Handling requires PPE due to potential respiratory sensitization.