Category:
Other Specialized Reagents
CAS NO:
421-85-2
Standard:
In-house Standards,
Trifluoromethanesulfonamide (CAS 405-96-1) is a potent sulfonamide derivative widely utilized in pharmaceutical synthesis. Its core industrial process involves the direct fluorination of methanesulfonyl chloride followed by ammonolysis, yielding the CF₃SO₂NH₂ structure essential for introducing triflyl groups.
Strict storage below 25°C in dry, ventilated areas is mandatory. Operators must wear full PPE due to corrosive nature; avoid contact with skin and eyes. Do not ingest or inhale dust. Medical use is restricted to professional laboratory settings only.