Category:
Active Pharmaceutical Ingredients
CAS NO:
738-70-5
Standard:
BP,
Trimethoprim is a dihydrofolate reductase inhibitor used in antimicrobial therapy. Its sodium salt enhances water solubility for parenteral formulations. Key specifications include CAS 738-70-5 (free base) and CAS 41229-83-6 (sodium), with molecular formula C14H18N4O3.
Strict adherence to dosage limits required due to potential bone marrow suppression. Storage must maintain dry conditions below 25°C to prevent hydrolysis. Personal protective equipment is mandatory during handling to avoid skin absorption.