Category:
Intermediates&Fine Chemicals
CAS NO:
420-37-1
Standard:
USP,
Trimethyloxonium tetrafluoroborate (CAS 1498-65-7) is a potent methylating agent with the formula (CH₃)₃OBF₄. It is synthesized via the reaction of dimethyl ether with trimethylaluminum or similar precursors, serving as a critical reagent for introducing methyl groups into nucleophilic substrates under mild conditions.
Store in a dry, inert atmosphere below -20°C due to moisture sensitivity. Use appropriate PPE; avoid contact as it causes severe skin burns and eye damage. Do not use in clinical settings without rigorous purification protocols.