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Overview
Candesartan Cilexetil (CAS 154170-96-8) is a prodrug of the angiotensin II receptor blocker candesartan. Its synthesis involves esterification to enhance oral bioavailability. The molecular formula is C29H30N6O6.
Application
- Hypertension management in clinical therapy.
- Heart failure treatment to reduce cardiovascular mortality.
- Renal protection for diabetic nephropathy patients.
Precautions
Contraindicated in pregnancy due to fetal toxicity. Store below 25°C in dry conditions. Handle with PPE to avoid inhalation or skin contact during manufacturing.