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*The following content is generated by AI and is for reference only.
Overview
Trityl Losartan is a protected intermediate in the industrial synthesis of losartan, an angiotensin II receptor blocker. The process involves tritylation of losartan to facilitate purification and subsequent deprotection. Molecular Formula: C35H28N4O2. CAS No.: 137965-03-2.
Application
- Pharmaceutical Manufacturing: Serves as a key precursor for high-purity losartan production.
- Process Chemistry: Utilized in multi-step synthesis to protect functional groups during reactions.
- Quality Control: Used as a reference standard for analyzing reaction intermediates.
Precautions
Requires storage in cool, dry conditions away from moisture. Handle with appropriate PPE to avoid skin contact. Not for direct clinical use; strictly an industrial intermediate subject to GMP regulations.