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Overview
Umeclidinium Bromide is a long-acting muscarinic antagonist (LAMA) synthesized via quaternization of tropane derivatives. It serves as the active pharmaceutical ingredient for chronic obstructive pulmonary disease management, with molecular formula C20H31BrNO2 and CAS No. 1196745-87-3.
Application
- Respiratory Therapeutics: Maintenance treatment of bronchospasm in COPD patients.
- Pulmonary Care: Component of fixed-dose combination inhalers for once-daily dosing.
- Pharmaceutical Manufacturing: Bulk API production for dry powder inhaler formulations.
Precautions
Contraindicated in severe hypersensitivity to atropine derivatives. Store under controlled room temperature in moisture-proof containers. Avoid direct contact due to potential anticholinergic effects; use appropriate PPE during handling.