Jiangsu Aidea Pharmaceutical Co., Ltd. offers a wide range of products which includes Urokinase. It is known as a urokinase-type plasminogen activator (uPA), which is a serine protease extracted and purified from human urine. It can activate the endogenous fibrinolysis system and convert plasminogen into plasmin, which can dissolve intravascular fibrin clots. Its finished formulation is mainly used for thrombolytic therapy of thromboembolic diseases. Please contact us for more information.
Urokinase is a serine protease enzyme utilized primarily as a thrombolytic agent. It catalyzes the conversion of plasminogen to plasmin, facilitating clot dissolution. The substance is typically produced via fermentation of human embryonic kidney cells or recombinant DNA technology. Its chemical structure is defined by the molecular formula C106H175N29O33S4 and CAS No. 9002-73-3.
Strictly contraindicated in patients with active internal bleeding or recent intracranial surgery. Storage requires refrigeration at 2°C to 8°C to maintain enzymatic stability. Handling demands PPE due to potential allergenicity and high potency risks.