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Overview
Valganciclovir Hydrochloride is a prodrug of ganciclovir, synthesized via esterification to enhance oral bioavailability. Its molecular formula is C13H21N5O4·HCl, with CAS No. 160014-72-8.
Application
- Prevention and treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients.
- Management of CMV prophylaxis following solid organ transplantation.
- Industrial production requires GMP-grade synthesis for pharmaceutical API distribution.
Precautions
Contraindicated in pregnancy due to teratogenic risks. Store below 25°C in dry conditions. Personnel must handle the powder with respiratory protection to avoid inhalation hazards.