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Overview
Valganciclovir Hydrochloride is the L-valyl ester prodrug of ganciclovir, primarily manufactured via enzymatic or chemical acylation. It serves as a critical antiviral agent with molecular formula C13H21N6O7P and CAS 159454-52-7.
Application
- Treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients.
- Prevention of CMV disease in solid organ transplant recipients.
- Oral therapy for pediatric congenital CMV infections.
Precautions
Contraindicated in hypersensitive individuals; requires strict renal function monitoring due to nephrotoxicity risks. Store below 25°C in dry conditions to maintain stability.