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Overview
Valsartan is a non-peptide angiotensin II receptor antagonist used in hypertension and heart failure management. Synthesized via cyclization and coupling reactions, its molecular formula is C24H29N5O3 (CAS: 137862-53-4).
Application
- Pharmaceutical API: Primary ingredient for antihypertensive tablets.
- Cardiovascular Therapy: Treatment of chronic heart failure post-MI.
- Renal Protection: Management of diabetic nephropathy complications.
Precautions
Contraindicated in pregnancy due to fetal toxicity. Store in cool, dry conditions below 25°C. Personnel must wear PPE to prevent inhalation or skin contact during handling.