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Overview
Velpatasvir is a direct-acting antiviral agent used in hepatitis C treatment. Its molecular formula is C27H19ClF3N5O4 (CAS No. 1365889-20-2). The compound features a pyrazine core synthesized via advanced organic coupling processes.
Application
- Hepatology: Combined with sofosbuvir for treating chronic HCV genotypes 1-6.
- Pharmaceutical Manufacturing: API production for fixed-dose combination tablets.
- Global Health Programs: Procurement by WHO for generic formulation distribution.
Precautions
Strictly contraindicated in severe hepatic impairment without monitoring. Store under controlled room temperature away from moisture. Handle with PPE to avoid dermal absorption during bulk processing.