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Overview
Vindesine Sulfate is a semi-synthetic vinca alkaloid derivative produced via chemical modification of vindoline. Its molecular formula is C46H58N4O10·H2SO4 and CAS number is 59266-38-1.
Application
- Oncology: Used as an antineoplastic agent for treating acute leukemia and soft tissue sarcomas.
- Chemotherapy Regimens: Combined with other cytotoxic drugs to inhibit microtubule assembly in rapidly dividing cells.
Precautions
Strictly contraindicated for patients with severe bone marrow suppression. Requires storage below 25°C in dry, light-resistant conditions. Handling mandates PPE due to potential carcinogenicity and neurotoxicity risks.