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Overview
Vismodegib is a targeted small-molecule inhibitor of the Hedgehog signaling pathway, primarily synthesized via multi-step organic coupling. Its molecular formula is C24H26FN5O2S with CAS No. 913927-70-7.
Application
- Oncology: Treatment of advanced basal cell carcinoma.
- Research: Preclinical studies on tumor progression mechanisms.
- Pharmaceutical Manufacturing: API production for oncology formulations.
Precautions
Strictly contraindicated in pregnancy due to teratogenic risks. Requires storage at controlled room temperature (20-25°C) in moisture-proof containers. Personnel must utilize appropriate PPE during handling to prevent dermal absorption.