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Overview
Volasertib (PD-0332991) is an investigational small-molecule inhibitor targeting Polo-like kinase 1 and 2. It features the molecular formula C24H26N8O5 and CAS No. 1247686-86-1, synthesized via multi-step organic coupling.
Application
- Targeted oncology therapy for acute myeloid leukemia.
- Combination chemotherapy with cytarabine in clinical trials.
- Research tool for cell cycle regulation studies.
Precautions
Restricted to clinical settings under strict physician supervision. Store at -20°C in airtight containers away from light. Handle with PPE due to potential cytotoxicity.