Name: Vonoprazan Fumarate
Alias: TAK-438; 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine,(E)-4-oxopent-2-enoic acid; CAS No.: 1260141-27-2
Molecular formula: C21H20FN3O6S
Molecular weight: 461.46300
Exact mass: 461.10600
PSA: 146.97000
LogP: 3.82910
Vonoprazan Fumate is a potassium-competitive acid blocker (P-CAB) used in pharmaceutical manufacturing. Its molecular formula is C16H18F2N4O5S, with CAS No. 1379039-44-3. The compound features high stability and rapid onset compared to traditional PPIs.
Contraindicated in patients with known hypersensitivity to vonoprazan or fumaric acid. Store in a cool, dry place below 25°C protected from light. Clinical use requires monitoring of liver function and potential drug-drug interactions involving CYP enzymes.