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Overview
Vorinostat is a histone deacetylase (HDAC) inhibitor developed for oncology. Its molecular formula is C14H20N2O3 and CAS number is 149649-57-0. The core synthesis involves condensation of 4-amino-N-hydroxybenzamide with specific fatty acid derivatives.
Application
- Oncology Manufacturing: Bulk API production for cutaneous T-cell lymphoma treatments.
- Research Chemicals: Supply for in vitro HDAC inhibition studies.
- Pharmaceutical Formulation: Ingredient for capsule and tablet dosage forms.
Precautions
Strictly limit use to approved indications under clinical supervision. Store in sealed containers at controlled room temperature, protected from moisture and light. Handle with appropriate PPE to avoid inhalation or skin contact.