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Overview
Voxilaprevir INT refers to the intermediate active moiety used in synthesizing voxelaprevir, a direct-acting antiviral (DAA). Its core process involves advanced chiral synthesis and peptide coupling. Molecular formula: C45H67N9O10S; CAS No.: 1486297-54-6.
Application
- Pharmaceutical Manufacturing: Critical API precursor for hepatitis C virus (HCV) treatment.
- R&D Laboratories: Used in mechanism studies of NS3/4A protease inhibition.
- Quality Control: Reference standard for verifying final drug substance purity.
Precautions
Must be stored under inert atmosphere at -20°C to prevent hydrolysis. Strict PPE is required during handling due to potential mutagenicity. Clinical use is restricted to combination therapy with sofosbuvir and velpatasvir only.