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Overview
Zafirlukast is a selective leukotriene receptor antagonist (LTRA) synthesized via condensation of 2-iodo-5-chlorobenzoic acid derivatives. Its molecular formula is C24H21NO6S with CAS number 107868-38-8. The core process involves high-purity crystallization to ensure API stability.
Application
- Pharmaceutical Manufacturing: Production of oral tablets for chronic asthma management.
- Respiratory Therapy: Prophylactic treatment of bronchoconstriction in allergic rhinitis.
- R&D Sector: Active pharmaceutical ingredient (API) sourcing for clinical trials.
Precautions
Contraindicated for acute asthma attacks; requires monitoring of hepatic function. Store in sealed containers below 25°C, protected from light and moisture to maintain chemical integrity.