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Overview
Zoledronic Acid Disodium Tetrahydrate is a potent nitrogen-containing bisphosphonate synthesized via phosphoramidite chemistry. Its molecular formula is C5H12N2O7P2Na2·4H2O, with CAS No. 166087-69-4.
Application
- Oncology: Management of hypercalcemia of malignancy.
- Osteoporosis: Treatment to reduce fracture risk in postmenopausal women.
- Bone Metastasis: Prevention of skeletal-related events in solid tumors.
Precautions
Contraindicated in severe renal impairment and pregnancy. Requires strict infusion protocols to prevent hypocalcemia. Store in dry conditions below 25°C to maintain hydrate stability.