Category:
Prophylactic Biological Products
CAS NO:
571190-30-2
Standard:
In-house Standards,
A member of the class of pyridopyrimidines that is 2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7-one bearing additional methyl, acetyl and cyclopentyl substituents at positions 5, 6 and 8 respectively. It is used in combina ion with letrozole for the treatment of metastatic breast cancer.
Palbociclib is a potent, selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). Synthesized via advanced organic coupling processes, its molecular formula is C27H30N6O3S with CAS No. 982271-28-5.
Strictly store below 25°C in dry, inert atmospheres to maintain stability. Handle with appropriate PPE due to potential cytotoxicity; avoid inhalation or skin contact during industrial processing.