(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride is an important intermediate for Ticagrelor.
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Overview
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride is a chiral intermediate for pharmaceutical synthesis, primarily used to construct fluorinated cyclopropyl scaffolds. Its standard specification includes the molecular formula C9H9ClF2N and CAS No. 1056783-55-3.
Application
- Medicinal Chemistry: Precursor for antiviral and CNS-active drug candidates.
- Agrochemicals: Building block for novel fungicides with enhanced stability.
- Material Science: Used in developing specialized fluorinated polymers.
Precautions
Store under inert atmosphere at -20°C to prevent hydrolysis. Handle with appropriate PPE as it may cause severe skin irritation and respiratory sensitization. Avoid contact with strong oxidizers.