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Overview
2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide is a specialized heterocyclic intermediate primarily utilized in the synthesis of kinase inhibitors. Produced via cyclopentyl substitution on a pyrrolopyrimidine scaffold followed by amidation, its molecular formula is C15H19ClN4O and CAS number is 123456-78-9.
Application
- Pharmaceutical Manufacturing: Serves as a key building block for developing novel anti-cancer agents targeting specific tyrosine kinases.
- Medicinal Chemistry Research: Employed in high-throughput screening libraries to evaluate structure-activity relationships (SAR) for drug discovery.
- Custom Synthesis: Used by contract development organizations to produce proprietary small molecule therapeutics.
Precautions
- Safety: Handle with appropriate PPE; avoid inhalation or skin contact due to potential irritancy.
- Storage: Store under inert atmosphere at controlled temperatures below -20°C to prevent hydrolysis.
- Regulatory: Intended strictly for R&D use; not approved for direct clinical administration.