Category:
Intermediates&Fine Chemicals
CAS NO:
850140-72-6
Standard:
In-house Standards,
| Product Name: | Afatinib | ||
| Product Code: | TY2018003 | ||
| Cas No.: | 850140-72-6 | ||
| Molecular Formula: | C24H25N5O3FCl | ||
| Molecular Weight: | 485.9384 | ||
| Purity: | 99% | ||
| Appearance: | white powder | ||
Afatinib is a second-generation tyrosine kinase inhibitor (TKI) designed for oral administration. It irreversibly binds to ErbB family receptors, including EGFR and HER2. The chemical structure corresponds to the molecular formula C26H27ClFN5O4 with CAS registry number 801888-51-9.
Storage requires controlled room temperature in a dry, light-resistant environment. Clinical use mandates monitoring for interstitial lung disease, severe diarrhea, and dermatological reactions. Handling requires appropriate PPE to prevent dermal absorption and inhalation exposure.