Category:
Prophylactic Biological Products
CAS NO:
1256580-46-7
Standard:
In-house Standards,
Alectinib (CH5424802) is an efficient ALK inhibitor. Its IC50 is 1.9nM and it is sensitive to the L1196M mutant, which is highly selective for ALK than PF-02341066, NVP-TAE684 and PHA-E429.
Alectinib is a potent, selective ALK inhibitor used in oncology. It features high brain penetration and is manufactured via advanced organic synthesis. Molecular formula: C28H30N4O3; CAS No.: 1222900-56-8.
Contraindicated in patients with severe hepatic impairment. Requires strict temperature control during storage (2°C–8°C). Monitor liver enzymes and QT interval regularly; avoid use in pregnancy.