Apixaban is an oral selective activated Xa factor inhibitor and can prevent thrombin generation and thrombosis.
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Overview
Apixaban is a direct Factor Xa inhibitor used in anticoagulant therapy. Manufactured via multi-step organic synthesis, its molecular formula is C21H26N5O4S and CAS number is 376780-76-6.
Application
- Prevention of stroke in non-valvular atrial fibrillation.
- Treatment of deep vein thrombosis (DVT) and pulmonary embolism.
- Post-operative prophylaxis following hip or knee replacement surgery.
Precautions
Contraindicated in patients with active pathological bleeding. Store in tightly sealed containers at controlled room temperature (20-25°C) to maintain stability and prevent degradation.