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Overview
Canagliflozin hemihydrate is the hydrated form of a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It is synthesized via multi-step organic coupling and crystallized to achieve specific hydration stability. The molecular formula is C28H31CaNO9·0.5H2O, with CAS No. 864073-79-4.
Application
- Pharmaceutical manufacturing for Type 2 diabetes management
- API production for SGLT2 inhibitor formulations
- Research supply for metabolic syndrome studies
Precautions
Store in cool, dry conditions below 25°C to prevent hydration loss or degradation. Handle with standard PPE to avoid inhalation or skin contact. Contraindicated in patients with severe renal impairment or history of hypersensitivity.