Appearance:
Colourless solid
Molecular Weight:
359.35
Density:
1.841g/cm3
Boiling Point:
437.874°C at 760 mmHg
Melting Point:
110-121 deg C
Flash Point:
218.619°C
Refractive index:
1.7
Solubility:
In water, 26 mg/mL at 20 deg C
*The following content is generated by AI and is for reference only.
Overview
Capecitabine is an oral prodrug of 5-fluorouracil, primarily synthesized via enzymatic or chemical conversion pathways. Its molecular formula is C15H22FN3O6 with CAS number 154361-50-9.
Application
- Oncology: First-line treatment for metastatic breast cancer.
- Gastroenterology: Adjuvant therapy for colorectal carcinoma.
- Palliative Care: Management of advanced gastric cancer cases.
Precautions
Strictly contraindicated in patients with DPD deficiency. Store at controlled room temperature (20-25°C) away from moisture. Handle with PPE due to potential teratogenicity and cytotoxic risks.