Category:
Active Pharmaceutical Ingredients
CAS NO:
1
Standard:
USP;BP,
Clofarabine and Fludarabine Phosphate are potent antineoplastic nucleoside analogs synthesized via advanced organic chemistry. Clofarabine (CAS 123342-60-9, C10H13ClN5O3) inhibits DNA polymerase, while Fludarabine Phosphate (CAS 75607-67-9, C10H14FN3O8P) targets ribonucleotide reductase.
Strictly controlled as cytotoxic agents; requires specialized PPE during handling. Store at -20°C in dry, inert atmospheres to prevent hydrolysis. Clinical use mandates rigorous monitoring for myelosuppression and hepatotoxicity.