Category:
Intermediates&Fine Chemicals
CAS NO:
877399-52-5
Standard:
In-house Standards,
| Product Name: | Crizotinib | ||
| Product Code: | TY2018005 | ||
| Cas No.: | 877399-52-5 | ||
| Molecular Formula: | C21H22Cl2FN5O | ||
| Purity: | 99% | ||
| Appearance: | White powder | ||
Crizotinib (CAS 871702-17-3) is a small-molecule tyrosine kinase inhibitor with the molecular formula C21H25Cl2N3O. It is synthesized via multi-step organic coupling reactions targeting specific anaplastic lymphoma kinase (ALK) and mesenchymal-epithelial transition factor (MET) pathways.
Strictly contraindicated for patients with severe hepatic impairment without dose adjustment. Requires storage in controlled environments at 2-8°C to maintain chemical stability. Personnel must utilize full PPE during handling to prevent dermal absorption and respiratory exposure.