A C-glycosyl compound consisting of a beta-glucosyl residue having a (4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl group at the anomeric centre. A sodium-glucose co-transporter 2 inhibitor u ed as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
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Overview
Empagliflozin is a selective SGLT2 inhibitor synthesized via multi-step organic coupling. Its molecular formula is C25H31NO9S with CAS No. 864079-34-3.
Application
- Pharmaceutical manufacturing for Type 2 diabetes mellitus treatment.
- Cardiovascular risk reduction in adult patients with chronic heart failure.
- Kidney protection therapy for diabetic nephropathy progression.
Precautions
Contraindicated in severe renal impairment and type 1 diabetes. Store below 25°C in dry, light-proof conditions. Handle with PPE to avoid dermal absorption during bulk processing.