Category:
Chiral Intermediates
CAS NO:
183319-69-9
Standard:
ChP,
Treatment of leukemia
Erlotinib hydrochloride is a potent, oral small-molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. Manufactured via multi-step organic synthesis and crystallization, its molecular formula is C21H22ClN7O·HCl with CAS No. 183321-74-6.
Contraindicated in patients with severe hypersensitivity to erlotinib or excipients. Storage requires keeping containers tightly closed at 20°C to 25°C in a dry environment. Personnel must utilize appropriate PPE to prevent inhalation or skin contact during handling.