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Overview
Ezetimibe is a cholesterol absorption inhibitor with the molecular formula C24H29NO5 and CAS No. 163222-98-6. It is synthesized via condensation reactions involving 4-chloro-3-[(3-fluorophenyl)methyl]-phenoxyacetic acid derivatives.
Application
- Pharmaceutical industry: Used as an active pharmaceutical ingredient (API) in combination with statins for treating hypercholesterolemia.
- Cardiovascular health: Reduces LDL-C levels by inhibiting intestinal cholesterol absorption.
Precautions
Contraindicated in patients with active liver disease or hypersensitivity to Ezetimibe. Store in a cool, dry place below 25°C protected from light. Ensure proper PPE during handling to avoid inhalation or skin contact.