Fingolimod is a sphingosine-l-phosphate (S1PR) receptor modulator. After phosphorylation, It is bound to s1P receptor that is on the surface of lymphocyte, which will change lymphocyte migration, and promote cells into the lymphatic tissue, and prevent lymphocytes from leaving the lymphoid tissue and get into the graft
*The following content is generated by AI and is for reference only.
Overview
Fingolimod hydrochloride is a sphingosine kinase inhibitor used in pharmaceutical synthesis. The core process involves precise chemical modification to ensure high purity. Molecular Formula: C15H24ClNO2; CAS No.: 79860-69-6.
Application
- Neurology: Treatment of relapsing forms of multiple sclerosis (RMS).
- R&D: Clinical trials for autoimmune disorder modulation.
- Manufacturing: Active Pharmaceutical Ingredient (API) production.
Precautions
Strictly monitor heart rate during initiation. Store below 25°C in a dry, ventilated environment. Handle with PPE due to potential respiratory sensitization.