Category:
Other Specialized Reagents
CAS NO:
1012341-50-2
Standard:
In-house Standards,
LCZ696 Intermediate 1 is a critical pharmaceutical building block for the synthesis of sacubitril, a key component of the angiotensin receptor-neprilysin inhibitor LCZ696 (Entresto). This compound serves as the essential scaffold in sacubitril manufacturing via specific coupling reactions. The molecular formula is C24H25NO6, and its CAS number is 850177-74-9.
Storage requires cool, dry conditions below 25°C to prevent hydrolysis. Personnel must utilize PPE including nitrile gloves and safety goggles during handling due to potential irritancy. Strict adherence to regulatory guidelines is mandatory for clinical supply chains.