Category:
Other Specialized Reagents
CAS NO:
1038924-62-7
Standard:
In-house Standards,
LCZ696 intermediate 8 is a critical synthetic precursor for the antihypertensive drug sacubitril/valsartan (Entresto). Produced via catalytic hydrogenation of specific nitro-precursors, its molecular formula is C17H24N2O4 with CAS No. 1305422-93-8.
Requires strict storage below 25°C in dry, inert atmospheres to prevent hydrolysis. Personnel must utilize appropriate PPE due to potential skin irritation; not for direct clinical use without final formulation.