Category:
Active Pharmaceutical Ingredients
CAS NO:
1
Standard:
USP;BP,
Lecucovorin Calcium is the calcium salt of leucovorin, a reduced folate derivative used to rescue cells from antifolate toxicity. Manufactured via enzymatic or chemical reduction of folic acid followed by calcium salt formation, its molecular formula is C20H24CaN8O10 with CAS No. 58054-16-9.
Strictly contraindicated in patients with known hypersensitivity to leucovorin or calcium salts. Store in a cool, dry place below 25°C away from direct light. Clinical administration requires precise dosing calculations based on serum methotrexate levels to avoid masking hematological toxicity.