Category:
Prophylactic Biological Products
CAS NO:
NA
Standard:
In-house Standards,
Loperamide HCl and Simethicone is a fixed-dose combination pharmaceutical agent designed for the management of acute diarrhea accompanied by gastrointestinal gas. The synthesis involves chemical coupling of loperamide hydrochloride, an opioid receptor agonist, with simethicone, an anti-foaming agent. The molecular formula is C29H33Cl2N2O2S2C8H18SiO4, and CAS numbers are 6003-19-0 (Loperamide) and 9006-58-8 (Simethicone).
Strictly contraindicated in patients with infectious colitis or severe hepatic impairment. Storage requires controlled temperature below 25°C with low humidity protection to prevent hydrolysis of the active ingredients.