Category:
Prophylactic Biological Products
CAS NO:
NA
Standard:
In-house Standards,
Macitentan is a dual endothelin receptor antagonist (ERA) used in pulmonary arterial hypertension. Its core synthesis involves chiral resolution and amide coupling. The chemical formula is C21H25N5O4S with CAS number 290679-68-6.
Contraindicated in pregnancy due to teratogenicity; requires strict contraception protocols. Store below 25°C in dry, light-resistant conditions. Monitor liver enzymes and hemoglobin levels regularly during clinical use.