Category:
Active Pharmaceutical Ingredients
CAS NO:
441798-33-0
Standard:
In-house Standards,
Macitentan is a dual endothelin receptor antagonist (ERA) with high selectivity for ETA and ETB receptors. Its industrial synthesis involves complex heterocyclic coupling reactions. Molecular formula: C24H26N4O5S; CAS No.: 109786-52-9.
Contraindicated in pregnancy due to teratogenicity; requires strict contraception monitoring. Store below 25°C in dry, light-resistant conditions. Handle with PPE to prevent inhalation or skin contact during manufacturing.